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Exploring the Syndecan-Mediated Cellular Internalization of the SARS-CoV-2 Omicron Variant
SARS-CoV-2 variants evolve to rely more on heparan sulfate (HS) for viral attachment and subsequent infection. In our earlier work, we demonstrated that the Delta variant’s spike protein binds more strongly to HS compared to WT SARS-CoV-2, leading to enhanced cell internalization via syndecans (SDCs...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531417/ https://www.ncbi.nlm.nih.gov/pubmed/37762442 http://dx.doi.org/10.3390/ijms241814140 |