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Quantitative Evaluation of CFTR Gene Expression: A Comparison between Relative Quantification by Real-Time PCR and Absolute Quantification by Droplet Digital PCR

In the precision medicine era of cystic fibrosis (CF), therapeutic interventions, by the so-called modulators, target the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The levels of targetable CFTR proteins are a main variable in the success of patient-specific therapy. In turn...

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Detalles Bibliográficos
Autores principales: Bruno, Sabina Maria, Blaconà, Giovanna, Lo Cicero, Stefania, Castelli, Germana, Virgulti, Mariarita, Testino, Giancarlo, Pierandrei, Silvia, Fuso, Andrea, Cimino, Giuseppe, Ferraguti, Giampiero, Eramo, Adriana, Lucarelli, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531455/
https://www.ncbi.nlm.nih.gov/pubmed/37761921
http://dx.doi.org/10.3390/genes14091781