Bony Fish Arachidonic Acid 15-Lipoxygenases Exhibit Different Catalytic Properties than Their Mammalian Orthologs, Suggesting Functional Enzyme Evolution during Vertebrate Development

The human genome involves six functional arachidonic acid lipoxygenase (ALOX) genes and the corresponding enzymes (ALOX15, ALOX15B, ALOX12, ALOX12B, ALOXE3, ALOX5) have been implicated in cell differentiation and in the pathogenesis of inflammatory, hyperproliferative, metabolic, and neurological di...

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Detalles Bibliográficos
Autores principales: Roigas, Sophie, Kakularam, Kumar R., Rothe, Michael, Heydeck, Dagmar, Aparoy, Polamarasetty, Kuhn, Hartmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531496/
https://www.ncbi.nlm.nih.gov/pubmed/37762455
http://dx.doi.org/10.3390/ijms241814154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531496/
https://www.ncbi.nlm.nih.gov/pubmed/37762455
http://dx.doi.org/10.3390/ijms241814154

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