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Therapeutic Peptide RF16 Derived from CXCL8 Inhibits MDA-MB-231 Cell Invasion and Metastasis

Interleukin (IL)-8 plays a vital role in regulating inflammation and breast cancer formation by activating CXCR1/2. We previously designed an antagonist peptide, (RF16), to inhibits the activation of downstream signaling pathways by competing with IL-8 in binding to CXCR1/2, thereby inhibiting IL-8-...

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Detalles Bibliográficos
Autores principales: Chang, Chun-Ming, Chang, Chun-Chun, Lam, Ho Yin Pekkle, Peng, Shih-Yi, Lai, Yi-Hsuan, Hsiang, Bi-Da, Liao, Yu-Yi, Hsu, Hao-Jen, Jiang, Shinn-Jong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531501/
https://www.ncbi.nlm.nih.gov/pubmed/37762330
http://dx.doi.org/10.3390/ijms241814029