Restoring Angiotensin Type 2 Receptor Function Reverses PFOS-Induced Vascular Hyper-Reactivity and Hypertension in Pregnancy

Perfluorooctane sulfonic acid (PFOS) exposure during pregnancy induces hypertension with decreased vasodilatory angiotensin type-2 receptor (AT2R) expression and impaired vascular reactivity and fetal weights. We hypothesized that AT2R activation restores the AT1R/AT2R balance and reverses gestation...

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Detalles Bibliográficos
Autores principales: Dangudubiyyam, Sri Vidya, Bosse, Bradley, Yadav, Pankaj, Song, Ruolin, Hofmann, Alissa, Mishra, Jay S., Kumar, Sathish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531530/
https://www.ncbi.nlm.nih.gov/pubmed/37762482
http://dx.doi.org/10.3390/ijms241814180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531530/
https://www.ncbi.nlm.nih.gov/pubmed/37762482
http://dx.doi.org/10.3390/ijms241814180

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