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Restoring Angiotensin Type 2 Receptor Function Reverses PFOS-Induced Vascular Hyper-Reactivity and Hypertension in Pregnancy
Perfluorooctane sulfonic acid (PFOS) exposure during pregnancy induces hypertension with decreased vasodilatory angiotensin type-2 receptor (AT2R) expression and impaired vascular reactivity and fetal weights. We hypothesized that AT2R activation restores the AT1R/AT2R balance and reverses gestation...
Autores principales: | Dangudubiyyam, Sri Vidya, Bosse, Bradley, Yadav, Pankaj, Song, Ruolin, Hofmann, Alissa, Mishra, Jay S., Kumar, Sathish |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531530/ https://www.ncbi.nlm.nih.gov/pubmed/37762482 http://dx.doi.org/10.3390/ijms241814180 |
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