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Insights into Repeated Renal Injury Using RNA-Seq with Two New RPTEC Cell Lines

Renal proximal tubule epithelial cells (RPTECs) are a primary site for kidney injury. We created two RPTEC lines from CD-1 mice immortalized with hTERT (human telomerase reverse transcriptase) or SV40 LgT antigen (Simian Virus 40 Large T antigen). Our hypothesis was that low-level, repeated exposure...

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Detalles Bibliográficos
Autores principales: Merrick, B. Alex, Martin, Negin P., Brooks, Ashley M., Foley, Julie F., Dunlap, Paul E., Ramaiahgari, Sreenivasa, Fannin, Rick D., Gerrish, Kevin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531624/
https://www.ncbi.nlm.nih.gov/pubmed/37762531
http://dx.doi.org/10.3390/ijms241814228