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Interaction of Substrates with γ-Secretase at the Level of Individual Transmembrane Helices—A Methodological Approach
Intramembrane proteases, such as γ secretase, typically recruit multiple substrates from an excess of single-span membrane proteins. It is currently unclear to which extent substrate recognition depends on specific interactions of their transmembrane domains (TMDs) with TMDs of a protease. Here, we...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531681/ https://www.ncbi.nlm.nih.gov/pubmed/37762696 http://dx.doi.org/10.3390/ijms241814396 |