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SARS-CoV-2 Syncytium under the Radar: Molecular Insights of the Spike-Induced Syncytia and Potential Strategies to Limit SARS-CoV-2 Replication

SARS-CoV-2 infection induces non-physiological syncytia when its spike fusogenic protein on the surface of the host cells interacts with the ACE2 receptor on adjacent cells. Spike-induced syncytia are beneficial for virus replication, transmission, and immune evasion, and contribute to the progressi...

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Detalles Bibliográficos
Autores principales: Ali, Hashim, Naseem, Asma, Siddiqui, Zaheenul Islam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531702/
https://www.ncbi.nlm.nih.gov/pubmed/37763019
http://dx.doi.org/10.3390/jcm12186079