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Exploring Three Avenues: Chemo- and Regioselective Transformations of 1,2,4-Triketone Analogs into Pyrazoles and Pyridazinones

A convenient approach to substituted pyrazoles and pyridazinones based on 1,2,4-triketones is presented. Chemo- and regiocontrol in condensations of t-Bu, Ph-, 2-thienyl-, and CO(2)Et-substituted 1,2,4-triketone analogs with hydrazines are described. The direction of preferential nucleophilic attack...

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Detalles Bibliográficos
Autores principales: Edilova, Yulia O., Osipova, Ekaterina A., Slepukhin, Pavel A., Saloutin, Victor I., Bazhin, Denis N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531707/
https://www.ncbi.nlm.nih.gov/pubmed/37762539
http://dx.doi.org/10.3390/ijms241814234