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Hydroxychloroquine-Loaded Chitosan Nanoparticles Induce Anticancer Activity in A549 Lung Cancer Cells: Design, BSA Binding, Molecular Docking, Mechanistic, and Biological Evaluation

The current study describes the encapsulation of hydroxychloroquine, widely used in traditional medicine due to its diverse pharmacological and medicinal uses, in chitosan nanoparticles (CNPs). This work aims to combine the HCQ drug with CS NPs to generate a novel nanocomposite with improved charact...

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Detalles Bibliográficos
Autores principales: Elshami, Fawzia I., Shereef, Hadeer A., El-Mehasseb, Ibrahim M., Shaban, Shaban Y., van Eldik, Rudi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531786/
https://www.ncbi.nlm.nih.gov/pubmed/37762406
http://dx.doi.org/10.3390/ijms241814103