Cost-Efficient Detection of NTRK1/2/3 Gene Fusions: Single-Center Analysis of 8075 Tumor Samples

The majority of NTRK1, NTRK2, and NTRK3 rearrangements result in increased expression of the kinase portion of the involved gene due to its fusion to an actively transcribed gene partner. Consequently, the analysis of 5′/3′-end expression imbalances is potentially capable of detecting the entire spe...

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Detalles Bibliográficos
Autores principales: Romanko, Aleksandr A., Mulkidjan, Rimma S., Tiurin, Vladislav I., Saitova, Evgeniya S., Preobrazhenskaya, Elena V., Krivosheyeva, Elena A., Mitiushkina, Natalia V., Shestakova, Anna D., Belogubova, Evgeniya V., Ivantsov, Alexandr O., Iyevleva, Aglaya G., Imyanitov, Evgeny N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531831/
https://www.ncbi.nlm.nih.gov/pubmed/37762506
http://dx.doi.org/10.3390/ijms241814203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531831/
https://www.ncbi.nlm.nih.gov/pubmed/37762506
http://dx.doi.org/10.3390/ijms241814203

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