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Cost-Efficient Detection of NTRK1/2/3 Gene Fusions: Single-Center Analysis of 8075 Tumor Samples
The majority of NTRK1, NTRK2, and NTRK3 rearrangements result in increased expression of the kinase portion of the involved gene due to its fusion to an actively transcribed gene partner. Consequently, the analysis of 5′/3′-end expression imbalances is potentially capable of detecting the entire spe...
Autores principales: | Romanko, Aleksandr A., Mulkidjan, Rimma S., Tiurin, Vladislav I., Saitova, Evgeniya S., Preobrazhenskaya, Elena V., Krivosheyeva, Elena A., Mitiushkina, Natalia V., Shestakova, Anna D., Belogubova, Evgeniya V., Ivantsov, Alexandr O., Iyevleva, Aglaya G., Imyanitov, Evgeny N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531831/ https://www.ncbi.nlm.nih.gov/pubmed/37762506 http://dx.doi.org/10.3390/ijms241814203 |
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