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From Innate Immunity to Metabolic Disorder: A Review of the NLRP3 Inflammasome in Diabetes Mellitus

The role of the NLRP3 inflammasome is pivotal in the pathophysiology and progression of diabetes mellitus (DM), encompassing both type 1 (T1D), or type 2 (T2D). As part of the innate immune system, NLRP3 is also responsible for the chronic inflammation triggered by hyperglycemia. In both conditions,...

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Detalles Bibliográficos
Autores principales: Nițulescu, Iris Maria, Ciulei, George, Cozma, Angela, Procopciuc, Lucia Maria, Orășan, Olga Hilda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531881/
https://www.ncbi.nlm.nih.gov/pubmed/37762961
http://dx.doi.org/10.3390/jcm12186022