A High-Throughput Small-Angle X-ray Scattering Assay to Determine the Conformational Change of Plasminogen

Plasminogen (Plg) is the inactive form of plasmin (Plm) that exists in two major glycoforms, referred to as glycoforms I and II (GI and GII). In the circulation, Plg assumes an activation-resistant “closed” conformation via interdomain interactions and is mediated by the lysine binding site (LBS) on...

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Detalles Bibliográficos
Autores principales: Quek, Adam J., Cowieson, Nathan P., Caradoc-Davies, Tom T., Conroy, Paul J., Whisstock, James C., Law, Ruby H. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531915/
https://www.ncbi.nlm.nih.gov/pubmed/37762561
http://dx.doi.org/10.3390/ijms241814258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531915/
https://www.ncbi.nlm.nih.gov/pubmed/37762561
http://dx.doi.org/10.3390/ijms241814258

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