Silibinin Downregulates Types I and III Collagen Expression via Suppression of the mTOR Signaling Pathway

Keloid scars are fibro-proliferative conditions characterized by abnormal fibroblast proliferation and excessive extracellular matrix deposition. The mammalian target of the rapamycin (mTOR) pathway has emerged as a potential therapeutic target in keloid disease. Silibinin, a natural flavonoid isola...

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Detalles Bibliográficos
Autores principales: Choi, Sooyeon, Ham, Seoyoon, Lee, Young In, Kim, Jihee, Lee, Won Jai, Lee, Ju Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531945/
https://www.ncbi.nlm.nih.gov/pubmed/37762688
http://dx.doi.org/10.3390/ijms241814386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531945/
https://www.ncbi.nlm.nih.gov/pubmed/37762688
http://dx.doi.org/10.3390/ijms241814386

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