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Silibinin Downregulates Types I and III Collagen Expression via Suppression of the mTOR Signaling Pathway

Keloid scars are fibro-proliferative conditions characterized by abnormal fibroblast proliferation and excessive extracellular matrix deposition. The mammalian target of the rapamycin (mTOR) pathway has emerged as a potential therapeutic target in keloid disease. Silibinin, a natural flavonoid isola...

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Detalles Bibliográficos
Autores principales:	Choi, Sooyeon, Ham, Seoyoon, Lee, Young In, Kim, Jihee, Lee, Won Jai, Lee, Ju Hee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531945/ https://www.ncbi.nlm.nih.gov/pubmed/37762688 http://dx.doi.org/10.3390/ijms241814386

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