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Jaw Bone Invasion of Oral Squamous Cell Carcinoma Is Associated with Osteoclast Count and Expression of Its Regulating Proteins in Patients and Organoids

Aims: Oral squamous cell carcinoma (OSCC) frequently invades the jaw. The exact mechanism of bone invasion remains unclear. This study investigates (premature) osteoclasts and the expression of its differentiation regulating proteins RANKL, OPG and RANK in patients with OSCC. Methods: Resection spec...

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Detalles Bibliográficos
Autores principales: de Kort, Willem W. B., Haakma, Wisse E., van Es, Robert J. J., Gawlitta, Debby, Driehuis, Else, Gansevoort, Merel, Willems, Stefan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531999/
https://www.ncbi.nlm.nih.gov/pubmed/37762975
http://dx.doi.org/10.3390/jcm12186035