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Cytotoxic Potential of Novel Quinoline Derivative: 11-(1,4-Bisaminopropylpiperazinyl)5-methyl-5H-indolo[2,3-b]quinoline against Different Cancer Cell Lines via Activation and Deactivation of the Expression of Some Proteins

The current study evaluated the cytotoxic activity of 11-(1,4-bisaminopropylpiperazinyl)5-methyl-5H-indolo[2,3-b]quinoline (BAPPN), a novel derivative of 5-methyl-5H-indolo[2,3-b]quinoline, against hepatocellular carcinoma (HepG2), colon carcinoma (HCT-116), breast (MCF-7), and lung (A549) cancer ce...

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Detalles Bibliográficos
Autores principales: Abd Elrahman, Sara Fathy, Ahmed, Abdullah A. S., Abd Elsatar, Doaa, Elkady, Salma, Elgendy, Amira, Alnakeeb, Fatma, Elmongy, Elshaymaa I., Henidi, Hanan A., El-Gendy, Saad M., El Sayed, Ibrahim El Tantawy, El-Gokha, Ahmed A., Abd Eldaim, Mabrouk Attia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10532317/
https://www.ncbi.nlm.nih.gov/pubmed/37762637
http://dx.doi.org/10.3390/ijms241814336