Prediction of Amino Acid Substitutions in ABL1 Protein Leading to Tumor Drug Resistance Based on “Structure-Property” Relationship Classification Models

Drug resistance to anticancer drugs is a serious complication in patients with cancer. Typically, drug resistance occurs due to amino acid substitutions (AAS) in drug target proteins. The study aimed at developing and validating a new approach to the creation of structure-property relationships (SPR...

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Detalles Bibliográficos
Autores principales: Zhuravleva, Svetlana I., Zadorozhny, Anton D., Shilov, Boris V., Lagunin, Alexey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10532460/
https://www.ncbi.nlm.nih.gov/pubmed/37763211
http://dx.doi.org/10.3390/life13091807

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10532460/
https://www.ncbi.nlm.nih.gov/pubmed/37763211
http://dx.doi.org/10.3390/life13091807

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