Activation of a Silent Polyketide Synthase SlPKS4 Encoding the C(7)-Methylated Isocoumarin in a Marine-Derived Fungus Simplicillium lamellicola HDN13-430

Coumarins, isocoumarins and their derivatives are polyketides abundant in fungal metabolites. Although they were first discovered over 50 years ago, the biosynthetic process is still not entirely understood. Herein, we report the activation of a silent nonreducing polyketide synthase that encodes a...

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Detalles Bibliográficos
Autores principales: Yu, Jing, Liu, Xiaolin, Ma, Chuanteng, Li, Chen, Zhang, Yuhan, Che, Qian, Zhang, Guojian, Zhu, Tianjiao, Li, Dehai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10532586/
https://www.ncbi.nlm.nih.gov/pubmed/37755103
http://dx.doi.org/10.3390/md21090490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10532586/
https://www.ncbi.nlm.nih.gov/pubmed/37755103
http://dx.doi.org/10.3390/md21090490

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