Cargando…

Activation of a Silent Polyketide Synthase SlPKS4 Encoding the C(7)-Methylated Isocoumarin in a Marine-Derived Fungus Simplicillium lamellicola HDN13-430

Coumarins, isocoumarins and their derivatives are polyketides abundant in fungal metabolites. Although they were first discovered over 50 years ago, the biosynthetic process is still not entirely understood. Herein, we report the activation of a silent nonreducing polyketide synthase that encodes a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Jing, Liu, Xiaolin, Ma, Chuanteng, Li, Chen, Zhang, Yuhan, Che, Qian, Zhang, Guojian, Zhu, Tianjiao, Li, Dehai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10532586/ https://www.ncbi.nlm.nih.gov/pubmed/37755103 http://dx.doi.org/10.3390/md21090490

Ejemplares similares

Lipid-Lowering Polyketides from the Fungus Penicillium Steckii HDN13-279
por: Yu, Guihong, et al.
Publicado: (2018)

Antibacterial Polyketides from Antarctica Sponge-Derived Fungus Penicillium sp. HDN151272
por: Shah, Mudassir, et al.
Publicado: (2020)

Overexpression of Global Regulator PbrlaeA Leads to the Discovery of New Polyketide in Fungus Penicillium Brocae HDN-12-143
por: Wang, Lu, et al.
Publicado: (2020)

Antifungal Activity and Biocontrol Potential of Simplicillium lamellicola JC-1 against Multiple Fungal Pathogens of Oilseed Rape
por: Li, Wenting, et al.
Publicado: (2022)

Cytotoxic Tetrahydroxanthone Dimers from the Mangrove-Associated Fungus Aspergillus versicolor HDN1009
por: Yu, Guihong, et al.
Publicado: (2018)

Development of a Biofungicide Using a Mycoparasitic Fungus Simplicillium lamellicola BCP and Its Control Efficacy against Gray Mold Diseases of Tomato and Ginseng
por: Shin, Teak Soo, et al.
Publicado: (2017)

Anthraquinone Derivatives from a Marine-Derived Fungus Sporendonema casei HDN16-802
por: Ge, Xueping, et al.
Publicado: (2019)

Citreobenzofuran D–F and Phomenone A–B: Five Novel Sesquiterpenoids from the Mangrove-Derived Fungus Penicillium sp. HDN13-494
por: Wu, Qian, et al.
Publicado: (2022)

Antibacterial Cyclic Tripeptides from Antarctica-Sponge-Derived Fungus Aspergillus insulicola HDN151418
por: Sun, Chunxiao, et al.
Publicado: (2020)

Saliniquinone Derivatives, Saliniquinones G−I and Heraclemycin E, from the Marine Animal-Derived Nocardiopsis aegyptia HDN19-252
por: Zhou, Luning, et al.
Publicado: (2021)

New Glutamine-Containing Azaphilone Alkaloids from Deep-Sea-Derived Fungus Chaetomium globosum HDN151398
por: Sun, Chunxiao, et al.
Publicado: (2019)

An efficient marker recycling system for sequential gene deletion in a deep sea-derived fungus Acremonium sp. HDN16-126
por: Sun, Ruonan, et al.
Publicado: (2021)

Brasilterpenes A–E, Bergamotane Sesquiterpenoid Derivatives with Hypoglycemic Activity from the Deep Sea-Derived Fungus Paraconiothyrium brasiliense HDN15-135
por: Wang, Wenxue, et al.
Publicado: (2022)

Austalides S-U, New Meroterpenoids from the Sponge-Derived Fungus Aspergillus aureolatus HDN14-107
por: Peng, Jixing, et al.
Publicado: (2016)

The genus Simplicillium
por: Wei, De-Ping, et al.
Publicado: (2019)

Unusual Tetrahydropyridoindole-Containing Tetrapeptides with Human Nicotinic Acetylcholine Receptors Targeting Activity Discovered from Antarctica-Derived Psychrophilic Pseudogymnoascus sp. HDN17-933
por: Hou, Xuewen, et al.
Publicado: (2022)

An Overview of the Medicinally Important Plant Type III PKS Derived Polyketides
por: Bisht, Renu, et al.
Publicado: (2021)

Structure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13
por: Kim, Sun Kyung, et al.
Publicado: (2023)

Polyketide synthases of Diaporthe helianthi and involvement of DhPKS1 in virulence on sunflower
por: Ruocco, Michelina, et al.
Publicado: (2018)

Entomopathogenicity of Simplicillium lanosoniveum Isolated in Korea
por: Lim, Sung Yeol, et al.
Publicado: (2014)

The Interpretation of the Role of a Polyketide Synthase ClPKS18 in the Pathogenicity of Curvularia lunata
por: Lu, Zhixiang, et al.
Publicado: (2022)

Solution structure of the type I polyketide synthase Pks13 from Mycobacterium tuberculosis
por: Bon, Cécile, et al.
Publicado: (2022)

Metabolomic Analysis Demonstrates the Impacts of Polyketide Synthases PKS14 and PKS15 on the Production of Beauvericins, Bassianolide, Enniatin A, and Ferricrocin in Entomopathogen Beauveria bassiana
por: Toopaang, Wachiraporn, et al.
Publicado: (2023)

Identification of epipolythiodioxopiperazines HDN-1 and chaetocin as novel inhibitor of heat shock protein 90
por: Song, Xiaoping, et al.
Publicado: (2015)

Mycobacterium tuberculosis pks12 Produces a Novel Polyketide Presented by CD1c to T Cells
por: Matsunaga, Isamu, et al.
Publicado: (2004)

The polyketide synthase PKS15 has a crucial role in cell wall formation in Beauveria bassiana
por: Udompaisarn, Somsiri, et al.
Publicado: (2020)

Characterization of NRPS and PKS genes involved in the biosynthesis of SMs in Alternaria dauci including the phytotoxic polyketide aldaulactone
por: Courtial, Julia, et al.
Publicado: (2022)

Discovery of Two New Sorbicillinoids by Overexpression of the Global Regulator LaeA in a Marine-Derived Fungus Penicillium dipodomyis YJ-11
por: Yu, Jing, et al.
Publicado: (2019)

Evolutionary Dynamics Based on Comparative Genomics of Pathogenic Escherichia coli Lineages Harboring Polyketide Synthase (pks) Island
por: Suresh, Arya, et al.
Publicado: (2021)

Involvement of a Polyketide Synthetase ClPKS18 in the Regulation of Vegetative Growth, Melanin and Toxin Synthesis, and Virulence in Curvularia lunata
por: Gao, Jin-Xin, et al.
Publicado: (2017)

Presence of Polyketide Synthase (PKS) Gene and Counterpart Virulence Determinants in Klebsiella pneumoniae Strains Enhances Colorectal Cancer Progression In-Vitro
por: Kaur, Christina Parvinder, et al.
Publicado: (2023)

New Substituted Isocoumarins and Dihydroisocoumarins and their Cytotoxic Activities
por: Hampl, Veronika, et al.
Publicado: (2011)

An efficient Agrobacterium tumefaciens-mediated transformation method for Simplicillium subtropicum (Hypocreales: Cordycipitaceae)
por: Sbaraini, Nicolau, et al.
Publicado: (2021)

Simplicillium sinense sp. nov., a novel potential pathogen of tinea faciei
por: Yan, Qiu-Hong, et al.
Publicado: (2023)

Simplicilones A and B Isolated from the Endophytic Fungus Simplicillium subtropicum SPC3
por: Anoumedem, Elodie Gisèle M., et al.
Publicado: (2020)

Three novel insect-associated species of Simplicillium (Cordycipitaceae, Hypocreales) from Southwest China
por: Chen, Wan-Hao, et al.
Publicado: (2019)

6,8-Dihydroxy-3-methylisocoumarin
por: Shao, Chang-lun, et al.
Publicado: (2009)

Genus level analysis of PKS-NRPS and NRPS-PKS hybrids reveals their origin in Aspergilli
por: Theobald, Sebastian, et al.
Publicado: (2019)

MSP430 microcontroller basics
por: Davies, J H
Publicado: (2008)

MON-430 To B, or Not to B
por: Pradeep, Pallavi, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_fkkfutt3r1j52fu117bupg3ekg