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Pharmacogenetic Variants Associated with Fluoxetine Pharmacokinetics from a Bioequivalence Study in Healthy Subjects

Fluoxetine is one of the most prescribed antidepressants, yet it still faces challenges due to high intersubject variability in patient response. Mainly metabolized by the highly polymorphic gene CYP2D6, important differences in plasma concentrations after the same doses are found among individuals....

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Detalles Bibliográficos
Autores principales: Díaz-Tufinio, Carlos Alejandro, Palma-Aguirre, José Antonio, Gonzalez-Covarrubias, Vanessa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10532907/
https://www.ncbi.nlm.nih.gov/pubmed/37763120
http://dx.doi.org/10.3390/jpm13091352