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PNU-74654 Induces Cell Cycle Arrest and Inhibits EMT Progression in Pancreatic Cancer

Background and Objectives: PNU-74654, a Wnt/β-catenin pathway inhibitor, has an antiproliferative effect on many cancer types; however, its therapeutic role in pancreatic cancer (PC) has not yet been demonstrated. Here, the effects of PNU-74654 on proliferation and cell cycle phase distribution were...

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Detalles Bibliográficos
Autores principales: Chien, Tai-Long, Wu, Yao-Cheng, Lee, Hsiang-Lin, Sung, Wen-Wei, Yu, Chia-Ying, Chang, Ya-Chuan, Lin, Chun-Che, Wang, Chi-Chih, Tsai, Ming-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10532988/
https://www.ncbi.nlm.nih.gov/pubmed/37763649
http://dx.doi.org/10.3390/medicina59091531