Cargando…
The Role of Uric Acid in Human Health: Insights from the Uricase Gene
Uric acid is the final product of purine metabolism and is converted to allantoin in most mammals via the uricase enzyme. The accumulation of loss of function mutations in the uricase gene rendered hominoids (apes and humans) to have higher urate concentrations compared to other mammals. The loss of...
| Autor principal: | |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10532990/ https://www.ncbi.nlm.nih.gov/pubmed/37763176 http://dx.doi.org/10.3390/jpm13091409 |