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Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor

AMPA glutamate receptors (AMPARs), the primary mediators of excitatory neurotransmission in the brain, are either GluA2 subunit-containing and thus Ca(2+)-impermeable, or GluA2-lacking and Ca(2+)-permeable(1). Despite their prominent expression throughout interneurons and glia, their role in long-te...

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Detalles Bibliográficos
Autores principales: Zhang, Danyang, Ivica, Josip, Krieger, James M., Ho, Hinze, Yamashita, Keitaro, Stockwell, Imogen, Baradaran, Rozbeh, Cais, Ondrej, Greger, Ingo H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533411/
https://www.ncbi.nlm.nih.gov/pubmed/37704721
http://dx.doi.org/10.1038/s41586-023-06528-0