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Serpin E1 mediates the induction of renal tubular degeneration and premature senescence upon diabetic insult

As a leading cause of chronic kidney disease, diabetic kidney disease (DKD) involves insidious but progressive impairments of renal tubules, and is associated with premature renal aging. The underlying pathomechanisms remain elusive. Post hoc analyses of the publicly-available renal transcriptome re...

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Detalles Bibliográficos
Autores principales: Chen, Bo Han, Lu, Xiao Qing, Liang, Xian Hui, Wang, Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533493/
https://www.ncbi.nlm.nih.gov/pubmed/37758806
http://dx.doi.org/10.1038/s41598-023-43411-4