MRPS6 modulates glucose-stimulated insulin secretion in mouse islet cells through mitochondrial unfolded protein response

Lack of efficient insulin secretion from the pancreas can lead to impaired glucose tolerance (IGT), prediabetes, and diabetes. We have previously identified two IGT-associated single nucleotide polymorphisms (SNPs) rs62212118 and rs13052524 located at two overlapping genes: MRPS6 and SLC5A3. In this...

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Detalles Bibliográficos
Autores principales: Lin, Danhong, Yu, Jingwen, Lin, Leweihua, Ou, Qianying, Quan, Huibiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533529/
https://www.ncbi.nlm.nih.gov/pubmed/37758822
http://dx.doi.org/10.1038/s41598-023-43438-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533529/
https://www.ncbi.nlm.nih.gov/pubmed/37758822
http://dx.doi.org/10.1038/s41598-023-43438-7

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