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Proteomic and genetic analyses of influenza A viruses identify pan-viral host targets

Influenza A Virus (IAV) is a recurring respiratory virus with limited availability of antiviral therapies. Understanding host proteins essential for IAV infection can identify targets for alternative host-directed therapies (HDTs). Using affinity purification-mass spectrometry and global phosphoprot...

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Detalles Bibliográficos
Autores principales: Haas, Kelsey M., McGregor, Michael J., Bouhaddou, Mehdi, Polacco, Benjamin J., Kim, Eun-Young, Nguyen, Thong T., Newton, Billy W., Urbanowski, Matthew, Kim, Heejin, Williams, Michael A. P., Rezelj, Veronica V., Hardy, Alexandra, Fossati, Andrea, Stevenson, Erica J., Sukerman, Ellie, Kim, Tiffany, Penugonda, Sudhir, Moreno, Elena, Braberg, Hannes, Zhou, Yuan, Metreveli, Giorgi, Harjai, Bhavya, Tummino, Tia A., Melnyk, James E., Soucheray, Margaret, Batra, Jyoti, Pache, Lars, Martin-Sancho, Laura, Carlson-Stevermer, Jared, Jureka, Alexander S., Basler, Christopher F., Shokat, Kevan M., Shoichet, Brian K., Shriver, Leah P., Johnson, Jeffrey R., Shaw, Megan L., Chanda, Sumit K., Roden, Dan M., Carter, Tonia C., Kottyan, Leah C., Chisholm, Rex L., Pacheco, Jennifer A., Smith, Maureen E., Schrodi, Steven J., Albrecht, Randy A., Vignuzzi, Marco, Zuliani-Alvarez, Lorena, Swaney, Danielle L., Eckhardt, Manon, Wolinsky, Steven M., White, Kris M., Hultquist, Judd F., Kaake, Robyn M., García-Sastre, Adolfo, Krogan, Nevan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533562/
https://www.ncbi.nlm.nih.gov/pubmed/37758692
http://dx.doi.org/10.1038/s41467-023-41442-z