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Improvement of Learning and Memory by Elevating Brain D-Aspartate in a Mouse Model of Fragile X Syndrome

Fragile X syndrome (FXS) is an inherited human mental retardation that arises from expansion of a CGG repeat in the Fmr1 gene, causing loss of the fragile X mental retardation protein (FMRP). It is reported that N-methyl-D-aspartate receptor (NMDAR)-mediated facilitation of long-term potentiation (L...

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Detalles Bibliográficos
Autores principales: Li, Yu-Jiao, Zhang, Kun, Sun, Ting, Guo, Yan-Yan, Yang, Qi, Liu, Shui-Bing, Wu, Yu-Mei, Zhao, Ming-Gao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533629/
https://www.ncbi.nlm.nih.gov/pubmed/37453994
http://dx.doi.org/10.1007/s12035-023-03438-0