Different Chronic Stress Paradigms Converge on Endogenous TDP43 Cleavage and Aggregation

The TAR-DNA binding protein (TDP43) is a nuclear protein whose cytoplasmic inclusions are hallmarks of Amyotrophic Lateral Sclerosis (ALS). Acute stress in cells causes TDP43 mobilization to the cytoplasm and its aggregation through different routes. Although acute stress elicits a strong phenotype,...

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Detalles Bibliográficos
Autores principales: Candelise, Niccolò, Caissutti, Daniela, Zenuni, Henri, Nesci, Valentina, Scaricamazza, Silvia, Salvatori, Illari, Spinello, Zaira, Mattei, Vincenzo, Garofalo, Tina, Ferri, Alberto, Valle, Cristiana, Misasi, Roberta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533643/
https://www.ncbi.nlm.nih.gov/pubmed/37450246
http://dx.doi.org/10.1007/s12035-023-03455-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533643/
https://www.ncbi.nlm.nih.gov/pubmed/37450246
http://dx.doi.org/10.1007/s12035-023-03455-z

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