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Different Chronic Stress Paradigms Converge on Endogenous TDP43 Cleavage and Aggregation
The TAR-DNA binding protein (TDP43) is a nuclear protein whose cytoplasmic inclusions are hallmarks of Amyotrophic Lateral Sclerosis (ALS). Acute stress in cells causes TDP43 mobilization to the cytoplasm and its aggregation through different routes. Although acute stress elicits a strong phenotype,...
Autores principales: | Candelise, Niccolò, Caissutti, Daniela, Zenuni, Henri, Nesci, Valentina, Scaricamazza, Silvia, Salvatori, Illari, Spinello, Zaira, Mattei, Vincenzo, Garofalo, Tina, Ferri, Alberto, Valle, Cristiana, Misasi, Roberta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533643/ https://www.ncbi.nlm.nih.gov/pubmed/37450246 http://dx.doi.org/10.1007/s12035-023-03455-z |
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