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Inhibition of extracellular vesicle‐derived miR‐146a‐5p decreases progression of melanoma brain metastasis via Notch pathway dysregulation in astrocytes

Melanoma has the highest propensity of all cancers to metastasize to the brain with a large percentage of late‐stage patients developing metastases in the central nervous system (CNS). It is well known that metastasis establishment, cell survival, and progression are affected by tumour‐host cell int...

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Detalles Bibliográficos
Autores principales: Rigg, Emma, Wang, Jiwei, Xue, Zhiwei, Lunavat, Taral R., Liu, Guowei, Hoang, Tuyen, Parajuli, Himalaya, Han, Mingzhi, Bjerkvig, Rolf, Nazarov, Petr V., Nicot, Nathalie, Kreis, Stephanie, Margue, Christiane, Nomigni, Miléne Tetsi, Utikal, Jochen, Miletic, Hrvoje, Sundstrøm, Terje, Ystaas, Lars A. R., Li, Xingang, Thorsen, Frits
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533779/
https://www.ncbi.nlm.nih.gov/pubmed/37759347
http://dx.doi.org/10.1002/jev2.12363