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FEAST: A flow cytometry-based toolkit for interrogating microglial engulfment of synaptic and myelin proteins

Although engulfment is a hallmark of microglia function, fully validated platforms that facilitate high-throughput quantification of this process are lacking. Here, we present FEAST (Flow cytometric Engulfment Assay for Specific Target proteins), which enables interrogation of in vivo engulfment of...

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Detalles Bibliográficos
Autores principales: Dissing-Olesen, Lasse, Walker, Alec J., Feng, Qian, Barr, Helena J., Walker, Alicia C., Xie, Lili, Wilton, Daniel K., Das, Indrani, Benowitz, Larry I., Stevens, Beth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533836/
https://www.ncbi.nlm.nih.gov/pubmed/37758703
http://dx.doi.org/10.1038/s41467-023-41448-7