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Celf4 controls mRNA translation underlying synaptic development in the prenatal mammalian neocortex

Abnormalities in neocortical and synaptic development are linked to neurodevelopmental disorders. However, the molecular and cellular mechanisms governing initial synapse formation in the prenatal neocortex remain poorly understood. Using polysome profiling coupled with snRNAseq on human cortical sa...

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Detalles Bibliográficos
Autores principales: Salamon, Iva, Park, Yongkyu, Miškić, Terezija, Kopić, Janja, Matteson, Paul, Page, Nicholas F., Roque, Alfonso, McAuliffe, Geoffrey W., Favate, John, Garcia-Forn, Marta, Shah, Premal, Judaš, Miloš, Millonig, James H., Kostović, Ivica, De Rubeis, Silvia, Hart, Ronald P., Krsnik, Željka, Rasin, Mladen-Roko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533865/
https://www.ncbi.nlm.nih.gov/pubmed/37758766
http://dx.doi.org/10.1038/s41467-023-41730-8