Su(var)3-9 mediates age-dependent increase in H3K9 methylation on TDP-43 promoter triggering neurodegeneration

Aging progressively modifies the physiological balance of the organism increasing susceptibility to both genetic and sporadic neurodegenerative diseases. These changes include epigenetic chromatin remodeling events that may modify the transcription levels of disease-causing genes affecting neuronal...

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Detalles Bibliográficos
Autores principales: Marzullo, Marta, Romano, Giulia, Pellacani, Claudia, Riccardi, Federico, Ciapponi, Laura, Feiguin, Fabian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533867/
https://www.ncbi.nlm.nih.gov/pubmed/37758732
http://dx.doi.org/10.1038/s41420-023-01643-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533867/
https://www.ncbi.nlm.nih.gov/pubmed/37758732
http://dx.doi.org/10.1038/s41420-023-01643-3

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