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Estrogen receptor beta in astrocytes modulates cognitive function in mid-age female mice
Menopause is associated with cognitive deficits and brain atrophy, but the brain region and cell-specific mechanisms are not fully understood. Here, we identify a sex hormone by age interaction whereby loss of ovarian hormones in female mice at midlife, but not young age, induced hippocampal-depende...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533869/ https://www.ncbi.nlm.nih.gov/pubmed/37758709 http://dx.doi.org/10.1038/s41467-023-41723-7 |