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S100A2 induces epithelial–mesenchymal transition and metastasis in pancreatic cancer by coordinating transforming growth factor β signaling in SMAD4-dependent manner

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive tumor and is associated with a poor prognosis. Treatment strategies for PDAC are largely ineffective primarily because of delay in its diagnosis and limited efficacy of systematic treatment. S100A2 is associated with the proliferation, m...

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Detalles Bibliográficos
Autores principales: Chen, Qinbo, Guo, Hangcheng, Jiang, Haojie, Hu, Zujian, Yang, Xuejia, Yuan, Ziwei, Gao, Yuanyuan, Zhang, Ge, Bai, Yongheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533899/
https://www.ncbi.nlm.nih.gov/pubmed/37758734
http://dx.doi.org/10.1038/s41420-023-01661-1