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S100A2 induces epithelial–mesenchymal transition and metastasis in pancreatic cancer by coordinating transforming growth factor β signaling in SMAD4-dependent manner
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive tumor and is associated with a poor prognosis. Treatment strategies for PDAC are largely ineffective primarily because of delay in its diagnosis and limited efficacy of systematic treatment. S100A2 is associated with the proliferation, m...
Autores principales: | Chen, Qinbo, Guo, Hangcheng, Jiang, Haojie, Hu, Zujian, Yang, Xuejia, Yuan, Ziwei, Gao, Yuanyuan, Zhang, Ge, Bai, Yongheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533899/ https://www.ncbi.nlm.nih.gov/pubmed/37758734 http://dx.doi.org/10.1038/s41420-023-01661-1 |
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