Lung extracellular matrix modulates KRT5(+) basal cell activity in pulmonary fibrosis

Aberrant expansion of KRT5(+) basal cells in the distal lung accompanies progressive alveolar epithelial cell loss and tissue remodelling during fibrogenesis in idiopathic pulmonary fibrosis (IPF). The mechanisms determining activity of KRT5(+) cells in IPF have not been delineated. Here, we reveal...

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Detalles Bibliográficos
Autores principales: Hewitt, Richard J., Puttur, Franz, Gaboriau, David C. A., Fercoq, Frédéric, Fresquet, Maryline, Traves, William J., Yates, Laura L., Walker, Simone A., Molyneaux, Philip L., Kemp, Samuel V., Nicholson, Andrew G., Rice, Alexandra, Roberts, Edward, Lennon, Rachel, Carlin, Leo M., Byrne, Adam J., Maher, Toby M., Lloyd, Clare M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533905/
https://www.ncbi.nlm.nih.gov/pubmed/37758700
http://dx.doi.org/10.1038/s41467-023-41621-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533905/
https://www.ncbi.nlm.nih.gov/pubmed/37758700
http://dx.doi.org/10.1038/s41467-023-41621-y

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