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Oocytes orchestrate protein prenylation for mitochondrial function through selective inactivation of cholesterol biosynthesis in murine species

Emerging research and clinical evidence suggest that the metabolic activity of oocytes may play a pivotal role in reproductive anomalies. However, the intrinsic mechanisms governing oocyte development regulated by metabolic enzymes remain largely unknown. Our investigation demonstrates that geranylg...

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Detalles Bibliográficos
Autores principales: Sang, Yongjuan, Yang, Qiwen, Guo, Yueshuai, Liu, Xiaofei, Shen, Di, Jiang, Chen, Wang, Xinying, Li, Kang, Wang, Haiquan, Yang, Chaofan, Ding, Lijun, Sun, Haixiang, Guo, Xuejiang, Li, Chaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10534227/
https://www.ncbi.nlm.nih.gov/pubmed/37611828
http://dx.doi.org/10.1016/j.jbc.2023.105183