Sulforaphane induced NRF2 activation in obese pregnancy attenuates developmental redox imbalance and improves early-life cardiovascular function in offspring

In adverse pregnancy a perturbed redox environment is associated with abnormal early-life cardiovascular development and function. Previous studies have noted alterations in the expression and/or activity of Nuclear Factor E2 Related Factor 2 (NRF2) and its antioxidant targets during human gestation...

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Detalles Bibliográficos
Autores principales: Psefteli, Paraskevi-Maria, Morris, Jessica K., Ehler, Elisabeth, Smith, Lorna, Bowe, James, Mann, Giovanni E., Taylor, Paul D., Chapple, Sarah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10534264/
https://www.ncbi.nlm.nih.gov/pubmed/37774548
http://dx.doi.org/10.1016/j.redox.2023.102883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10534264/
https://www.ncbi.nlm.nih.gov/pubmed/37774548
http://dx.doi.org/10.1016/j.redox.2023.102883

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