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Sulforaphane induced NRF2 activation in obese pregnancy attenuates developmental redox imbalance and improves early-life cardiovascular function in offspring
In adverse pregnancy a perturbed redox environment is associated with abnormal early-life cardiovascular development and function. Previous studies have noted alterations in the expression and/or activity of Nuclear Factor E2 Related Factor 2 (NRF2) and its antioxidant targets during human gestation...
Autores principales: | Psefteli, Paraskevi-Maria, Morris, Jessica K., Ehler, Elisabeth, Smith, Lorna, Bowe, James, Mann, Giovanni E., Taylor, Paul D., Chapple, Sarah J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10534264/ https://www.ncbi.nlm.nih.gov/pubmed/37774548 http://dx.doi.org/10.1016/j.redox.2023.102883 |
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