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Metformin-Loaded Chitosan Hydrogels Suppress Bladder Tumor Growth in an Orthotopic Mouse Model via Intravesical Administration

Our previous study found that the intravesical perfusion of metformin has excellent inhibitory effects against bladder cancer (BC). However, this administration route allows the drug to be diluted and excreted in urine. Therefore, increasing the adhesion of metformin to the bladder mucosal layer may...

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Detalles Bibliográficos
Autores principales: Zhang, Xingjian, Hu, Xin, Xie, Yijun, Xie, Lejing, Chen, Xiangyi, Peng, Mei, Li, Duo, Deng, Jun, Xiao, Di, Yang, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10534355/
https://www.ncbi.nlm.nih.gov/pubmed/37764495
http://dx.doi.org/10.3390/molecules28186720