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Metformin-Loaded Chitosan Hydrogels Suppress Bladder Tumor Growth in an Orthotopic Mouse Model via Intravesical Administration
Our previous study found that the intravesical perfusion of metformin has excellent inhibitory effects against bladder cancer (BC). However, this administration route allows the drug to be diluted and excreted in urine. Therefore, increasing the adhesion of metformin to the bladder mucosal layer may...
Autores principales: | Zhang, Xingjian, Hu, Xin, Xie, Yijun, Xie, Lejing, Chen, Xiangyi, Peng, Mei, Li, Duo, Deng, Jun, Xiao, Di, Yang, Xiaoping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10534355/ https://www.ncbi.nlm.nih.gov/pubmed/37764495 http://dx.doi.org/10.3390/molecules28186720 |
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