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Effect of Compaction Pressure on the Enzymatic Activity of Pancreatin in Directly Compressible Formulations

Tableting of biomolecules is a challenging formulation phase due to their sensitivity to various process parameters, such as compression pressure, process dynamics, or the temperature generated. In the present study, pancreatin was employed as a model enzyme mixture, which was formulated in tablet f...

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Detalles Bibliográficos
Autores principales: Zakowiecki, Daniel, Edinger, Peter, Hess, Tobias, Paszkowska, Jadwiga, Staniszewska, Marcela, Romanova, Svitlana, Garbacz, Grzegorz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10534463/
https://www.ncbi.nlm.nih.gov/pubmed/37765193
http://dx.doi.org/10.3390/pharmaceutics15092224