Genistein Suppresses IL-6 and MMP-13 to Attenuate Osteoarthritis in Obese Diabetic Mice

Type 2 diabetes mellitus and osteoarthritis (OA) often present as comorbidities. We examined the role of plasma IL-6, chondrocyte MMP-13, and col10a expression in the development of OA in obese diabetic mice. We further investigated dietary genistein and exercise training as potential mitigators of...

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Detalles Bibliográficos
Autores principales: Lopez, Janelle, Al-Nakkash, Layla, Broderick, Tom L., Castro, Monica, Tobin, Brielle, Plochocki, Jeffrey H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10534591/
https://www.ncbi.nlm.nih.gov/pubmed/37755294
http://dx.doi.org/10.3390/metabo13091014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10534591/
https://www.ncbi.nlm.nih.gov/pubmed/37755294
http://dx.doi.org/10.3390/metabo13091014

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