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Anti-Colorectal Cancer Activity of Solasonin from Solanum nigrum L. via Histone Deacetylases-Mediated p53 Acetylation Pathway

(1) Background: Solanum nigrum L. is a plant of the genus Solanum in the family Solanaceae and is commonly used to treat tumors. Solasonin (SS) is a steroidal alkaloid extracted from Solanum nigrum L. that has anti-colorectal cancer (CRC) activity. (2) Methods: Column chromatography, semi-preparativ...

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Detalles Bibliográficos
Autores principales: Lan, Xintian, Lu, Meng, Fang, Xiaoxue, Cao, Yiming, Sun, Mingyang, Shan, Mengyao, Gao, Wenyi, Wang, Yuchen, Yu, Wenbo, Luo, Haoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10534604/
https://www.ncbi.nlm.nih.gov/pubmed/37764423
http://dx.doi.org/10.3390/molecules28186649