Dynamic Ex Vivo Porcine Eye Model to Measure Ophthalmic Drug Penetration under Simulated Lacrimal Flow

Animal models are still used in the research and development of ophthalmic drug products, mainly due to the difficulty in simulating natural physiological conditions with in vitro models, as there is a lack of dynamic protection mechanisms. Therefore, developing alternative ophthalmic models that ev...

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Detalles Bibliográficos
Autores principales: Barbalho, Geisa N., Falcão, Manuel A., Lopes, Jefferson M. S., Lopes, Júlia M., Contarato, Jonad L. A., Gelfuso, Guilherme M., Cunha-Filho, Marcilio, Gratieri, Tais
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10534681/
https://www.ncbi.nlm.nih.gov/pubmed/37765293
http://dx.doi.org/10.3390/pharmaceutics15092325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10534681/
https://www.ncbi.nlm.nih.gov/pubmed/37765293
http://dx.doi.org/10.3390/pharmaceutics15092325

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