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Twin Screw Melt Granulation: A Single Step Approach for Developing Self-Emulsifying Drug Delivery System for Lipophilic Drugs

The current research aims to improve the solubility of the poorly soluble drug, i.e., ibuprofen, by developing self-emulsifying drug delivery systems (SEDDS) utilizing a twin screw melt granulation (TSMG) approach. Gelucire(®) 44/14, Gelucire(®) 48/16, and Transcutol(®) HP were screened as suitable...

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Detalles Bibliográficos
Autores principales: Nyavanandi, Dinesh, Mandati, Preethi, Narala, Sagar, Alzahrani, Abdullah, Kolimi, Praveen, Vemula, Sateesh Kumar, Repka, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10534719/
https://www.ncbi.nlm.nih.gov/pubmed/37765237
http://dx.doi.org/10.3390/pharmaceutics15092267